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Is it safe to take gabapentin before getting a tattoo? Can gabapentin completely eliminate tattoo. Web gabapentin will likely do nothing for the tattoo pain, it's not necessarily unsafe to take an anticonvulsant before a tattoo,. Web gabapentinoid drugs—specifically gabapentin (neurontin) and pregabalin (lyrica)—are increasingly. Reduces sharp pain from tattoo needle alternative to opioids for pain relief convenient dosing.